High Frequency
Some possible therapeutic uses, including cancer treatment, of the few megahertz frequency range
→ An introductory text will be included soon ...
↓ tables updated: 19/05/2024
Applied Fields - Experimental
High Frequency
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| F |  | Pulsed Radiofrequency Electromagnetic Fields as Modulators of Inflammation and Wound Healing in Primary Dermal Fibroblasts of Ulcers | 27.1 MHz |  | 2024-(14) | Erica Costantini, Lisa Aielli, Giulio Gualdi, Manuela Baronio, Paola Monari, Paolo Amerio, Marcella Reale |
| F | | Radiofrequency Electromagnetic Fields Cause Non-Temperature-Induced Physical and Biological Effects in Cancer Cells | 13.56 MHz |  | 2022-(20) | Peter Wust, Paraskevi D. Veltsista, Eva Oberacker, Prabhusrinivas Yavvari, Wolfgang Walther, Olof Bengtsson, Anja Sterner-Kock, Marie Weinhart, Florian Heyd, Patricia Grabowski, Sebastian Stintzing, Wolfgang Heinrich, Ulrike Stein, Pirus Ghadjar |
| F | | Evaluation of Cell Migration and Cytokines Expression Changes under the Radiofrequency Electromagnetic Field on Wound Healing In Vitro Model | 27.1 MHz | | 2022-(14) | Erica Costantini, Lisa Aielli, Federica Serra, Lorenzo De Dominicis, Katia Falasca, Pamela Di Giovanni, Marcella Reale |
| A |  | A Systematic Method to Explore Radio Frequency Non-Thermal Effect on the Growth of Saccharomyces cerevisiae | 1 MHz, 3.16 MHz, 10 MHz - (SAR 0.0024 W/kg) | | 2021-(1) | Duye Ye, Gabriel Cutter, Tom Caldwell, Sarah Harcum, Pingshan Wang |
| F | | Safety and Efficacy of amplitude-modulated radiofrequency electromagnetic fields in advanced hepatocellular carcinoma | 27.12 MHz (0.1 Hz to 150 KHz modulated, tumor specific) - (SAR 0.001 W/kg (body)) | | 2021-(13) | Arthur W. Blackstock, Al B. Benson, Masatoshi Kudo, Hugo Jimenez, Preeya F. Achari, Callum McGrath, Volker Kirchner, Lynne I. Wagner, Nathaniel S. O’Connell, Kathy Walker, Valerie K. Pasche, Ralph D’Agostino Jr., Alexandre Barbault, Boris Pasche |
| F |  | Non-thermal membrane effects of electromagnetic fields and therapeutic applications in oncology | - | | 2021-(17) | Peter Wust, Ulrike Stein, Pirus Ghadjar |
| F | | Repeated electromagnetic field stimulation lowers amyloid-β peptide levels in primary human mixed brain tissue cultures | 64 MHz - (SAR 0.4-0.9 W/kg) | | 2021-(13) | Felipe P. Perez, Bryan Maloney, Nipun Chopra, Jorge J. Morisaki, Debomoy K. Lahiri |
| A | | Pilot study on the therapeutic potential of radiofrequency magnetic fields: growth inhibition of implanted tumours in mice | 10 MHz - 0.002 mT | | 2020-(1) | Jukka Luukkonen, Jonne Naarala, Jukka Juutilainen, Frank Barnes, Carlos F. Martino |
| A | | Changes in the gene expression in mouse astrocytes induced by pulsed radiofrequency: A preliminary study | 0.48 MHz (pulsed) | | 2020-(1) | Kumiko Tanabe, Shigeo Takashim, Hiroki Iida |
| F | | Arabidopsis cryptochrome is responsive to Radiofrequency (RF) electromagnetic fields (plant) | 7 MHz - 0.002 mT | | 2020-(8) | Maria Albaqami, Merfat Hammad, Marootpong Pooam, Maria Procopio, Mahyar Sameti, Thorsten Ritz, Margaret Ahmad, Carlos F. Martino |
| A | | Acceleration of germination and early growth of plant seeds by high frequency and low intensity alternating electric fields | 100 MHz - 0.0066-2.653 mW/cm2 | | 2020-(1) | Sumihiro Koyama, Yasuyuki Tamura, Gen Ishikawa, Yoichi Ishikawa |
| F | | Tumour-specific amplitude-modulated radiofrequency electromagnetic fields induce differentiation of hepatocellular carcinoma via targeting Ca v 3.2 T-type voltage-gated calcium channels and Ca 2+ influx | 27.12 MHz (SAR 0.001-0.035 W/kg (body) 0.156-0.352 W/kg (1g)) | | 2019-(16) | Hugo Jimenez, Minghui Wang, Jacquelyn W. Zimmerman, Michael J. Pennison, Sambad Sharma, Trevor Surratt, Zhi-Xiang Xu, Ivan Brezovich, Devin Absher, Richard M. Myers, Barry De Young, David L. Caudell, Dongquan Chen, Hui-Wen Lo, Hui-Kuan Lin, Dwayne W. Godwin, Michael Olivier, Anand Ghanekar, Kui Chen, Lance D. Miller, Yijian Gong, Myles Capstick, Ralph B. D'Agostino, Jr, Reginald Munden, Philippe Merle, Alexandre Barbault, Arthur W. Blackstock, Herbert L. Bonkovsky, Guang-Yu Yang, Guangxu Jin, Liang Liu, Wei Zhang, Kounosuke Watabe, Carl F. Blackman, Boris C. Pasche |
| F | | Ca2+ and CACNA1H mediate targeted suppression of breast cancer brain metastasis by AM RF EMF | 27.12 MHz - (SAR 0.255 W/kg (brain)) | | 2019-(15) | Sambad Sharma, Shih-Ying Wu, Hugo Jimenez, Fei Xing, Dongqin Zhu, Yin Liu, Kerui Wu, Abhishek Tyagi, Dan Zhao, Hui-Wen Lo, Linda Metheny-Barlow, Peiqing Sun, John D. Bourland, Michael D. Chan, Alexandra Thomas, Alexandre Barbault, Ralph B. D'Agostino, Christopher T. Whitlow, Volker Kirchner, Carl Blackman, Boris Pasche, Kounosuke Watabe |
| F |  | Use of Pulsed Radiofrequency Electromagnetic Field (Prfe) Therapy for Pain Management and Wound Healing in Total Knee and Reverse Shoulder Prosthesis: Randomized and Double-blind Study | 27.12 MHz | | 2018-(7) | Nicola Bianchi, Federico Sacchetti, Matteo Mordà, Carmine Citarelli, Rodolfo Capanna, Stefano Giannotti |
| A | | Repeated Electromagnetic Field Stimulation in Aging and Health | 64 MHz - (SAR 0.6 W/kg) | | 2018-(1) | Felipe P. Perez, Jorge J. Morisaki, Joseph P. Bandeira |
| F | | In-vitro analysis of Quantum Molecular Resonance effects on human mesenchymal stromal cells | 4-64 MHz | | 2018-(17) | Sabrina Sella, Valentina Adami, Eliana Amati, Martina Bernardi, Katia Chieregato, Pamela Gatto, Martina Menarin, Alessandro Pozzato, Gianantonio Pozzato, Giuseppe Astori |
| F | | Resonant Radiofrequency Fields Damaging Saccharomyces Cerevisiae (yeast) | 28 MHz | | 2018-(3) | W. S. Dias, E. H. M. Liquer, L. C. Gontijo, T. A. Oakes, G. S. Dias, C. Marques, H. S. Chavez |
| A | | Amplitude-modulated radiofrequency electromagnetic fields target hepatocellular carcinoma stem cells through activation of Cav 3.2 T-type calcium channels | 27.12 MHz - (SAR 0.0002-0.001 W/kg) | | 2018-(1) | Hugo Jimenez, Minghui Wang, Jacquelyn W. Zimmerman, Michael J. Pennison, Sambad Sharma, Ivan Brezovich |
| A | | Biophysical control of the growth of Agrobacterium tumefaciens using extremely low frequency electromagnetic waves at resonance frequency (bacteria) | 10 MHz (1 Hz modulated) - 0.000669 mT | | 2017-(1) | M. Ali Fadel, Reem H. El-Gebaly, Shaimaa A. Mohamed, Ashraf M.M. Abdelbacki |
| F | | Pulsed electromagnetic fields in knee osteoarthritis: a double blind, placebo-controlled, randomized clinical trial | 27.12 MHz (1000 Hz pulsed) | | 2015-(8) | Gian Luca Bagnato, Giovanni Miceli, Natale Marino1 , Davide Sciortino, Gian Filippo Bagnato |
| F | | Pulsed Electromagnetic Fields Reduce Postoperative Interleukin-1β, Pain, and Inflammation: A Double- Blind, Placebo-Controlled Study in TRAM Flap Breast Reconstruction Patients | 27.12 MHz (2 Hz pulsed) - 0.0042 mW/cm (SAR 0.001 W/kg) | | 2015-(10) | Christine H. Rohde, Erin M. Taylor, Amanda Alonso, Jeffrey A. Ascherman, Krista L. Hardy, Arthur A. Pilla |
| F | | Effect of Pulsed Electromagnetic Field (PEMF) on Infarct Size and Inflammation After Cerebral Ischemia in Mice | 27.12 MHz (2 Hz pulsed) - (SAR 0.04 W/kg) | | 2014-(10) | Juan Carlos Pena-Philippides, Yirong Yang, Olga Bragina, Sean Hagberg, Edwin Nemoto, Tamara Roitbak |
| F | | Increases in microvascular perfusion and tissue oxygenation via pulsed electromagnetic fields in the healthy rat brain | 27.12-MHz (5 Hz pulsed) - 0.0095 mW/cm (SAR 0.04 W/kg) | | 2014-(10) | Denis E. Bragin, Gloria L. Statom, Sean Hagberg, Edwin M. Nemoto |
| F | | Inhibition of cellular proliferation and enhancement of hydrogen peroxide production in fibrosarcoma cell line by weak radio frequency magnetic fields | 10 MHz - 0.01 mT | | 2014-(5) | Pablo R.Castello, Iain Hill, Frank Sivo, Lucas Portelli, Frank Barnes, Robert Usselman, Carlos F. Martino |
| F | | The Effects of Non-Invasive Radiofrequency Treatment and Hyperthermia on Malignant and Nonmalignant Cells | 13.56 MHz | | 2014-(12) | Steven A. Curley, Flavio Palalon, Kelly E. Sanders, Nadezhda V. Koshkina |
| F | | Non-Thermal Radio Frequency Stimulation of Tubulin Polymerization in Vitro: A Potential Therapy for Cancer Treatment | - | | 2014-(23) | John T. Butters, Xavier A. Figueroa, Bennett Michael Butters |
| F | | Spin Biochemistry Modulates Reactive Oxygen Species (ROS) Production by Radio Frequency Magnetic Fields | 7 MHz - 0.01 mT | | 2014-(9) | Robert J. Usselman, Iain Hill, David J. Singel, Carlos F. Martino |
| F | | Targeted treatment of cancer with radiofrequency electromagnetic fields amplitude-modulated at tumor-specific frequencies | - | | 2013-(9) | Jacquelyn W. Zimmerman, Hugo Jimenez, Michael J. Pennison, Ivan Brezovich, Desiree Morgan, Albert Mudry, Frederico P. Costa , Alexandre Barbault, Boris Pasche |
| F | | Electromagnetic fields instantaneously modulate nitric oxide signaling in challenged biological systems | 27.12 MHz (2 Hz pused) - 0.0025 mT | | 2012-(4) | Arthur A. Pilla |
| F | | Radio Frequency Energy for Bioelectric Stimulation of Plants (ICR) | 1-50 MHz (16 Hz modulated) - max. 0.005 mT | | 2012- (207) | Pieter Johannes Jacobus van Zyl |
| F | | Cancer cell proliferation is inhibited by specific modulation frequencies | 27.12 MHz - (SAR 0.034 W/kg) | | 2012-(7) | J. W. Zimmerman, M. J. Pennison, I. Brezovich, N. Yi, C. T. Yang, R. Ramaker, D. Absher, R. M. Myers, N. Kuster, F. P. Costa, A. Barbault, B. Pasche |
| F | | Treatment of advanced hepatocellular carcinoma with very low levels of amplitude-modulated electromagnetic fields | 27.12 MHz (100 Hz-21kHz modulated) - (SAR max. 2 W/kg (10g)) | | 2011-(9) | F.P. Costa, A.C. de Oliveira, R. Meirelles, M.C.C. Machado, T. Zanesco, R Surjan, M.C. Chammas, M. de Souza Rocha, D. Morgan, A. Cantor, J. Zimmerman, I. Brezovich, N. Kuster, A. Barbault, B. Pasche |
| F | | Electromagnetic fields as first messenger in biological signaling: Application to calmodulin-dependent signaling in tissue repair | 27.12 MHz (pulsed) - (SAR 0.0001 W/kg) | | 2011-(10) | Arthur Pilla, Robert Fitzsimmons, David Muehsam, June Wu, Christine Rohde, Diana Casper |
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