Oxidative Stress and NADPH Oxidase Connecting Electromagnetic Fields, Cation Channels and Biological Effects

" ...the biochemical specifics of the biological mechanisms involving the generation of OS are unclear, with the most well studied mechanisms being those involving ion channels. The main hypothesis underlining these mechanisms portrays EMF (RF 900, 1800, 1900, 2450 MHz, ELF 0–3000 Hz) exerting their oscillatory forces on every free ion on both sides of any biological membrane, thereby causing the ions, cations, in particular, to pass through at abnormal rates. Such abnormal cation movement can alter the biochemical properties of membranes and can cause deterioration of cation channel functions, especially those of the voltage-gated (VGC) ones [2,3,4,5,6,7,8]. These, in turn, can trigger an increase of OS, leading to the impairment of most cellular functions and DNA damage [9,10] as well as to numerous associated diseases including carcinogenesis [11,12,13]." {Credits 1}

{Credits 1} 🎪 Georgiou, C.D.; Margaritis, L.H. Oxidative Stress and NADPH Oxidase: Connecting Electromagnetic Fields, Cation Channels and Biological Effects. Int. J. Mol. Sci. 2021, 22, 10041. © 2021 The Author(s). This article is licensed under a Creative Commons Attribution 4.0 International License.