Probing the origins of 1800 MHz radio frequency electromagnetic radiation induced damage in mouse immortalized germ cells and spermatozoa in vitro

" This study demonstrated that a 4 h exposure is capable of inducing the generation of mitochondrial reactive oxygen species (ROS) in populations of GC1 (7 vs 18 %; p < 0.001) and GC2 cells (11.5 vs 16 %; p < 0.01), identifying Complex III of the electron transport chain (ETC) as the potential source of electrons producing ROS. ... exposure to RF-EMR at 0.15 W/kg for 3 hours did induce significant DNA fragmentation in spermatozoa (that was no longer significant after 4 h), assessed by the alkaline comet assay (p < 0.05). Furthermore, this fragmentation was accompanied by an induction of oxidative DNA damage in the form of 8-hydroxy-2’-deoxyguanosine, which was significant (p < 0.05) after spermatozoa were exposed to RF-EMR for 4 h. At this exposure time point, a decline in sperm motility (p < 0.05) was also observed." {Credits 1}

{Credits 1} 🎪 Houston BJ, Nixon B, King BV, Aitken RJ and De Iuliis GN (2018) Probing the Origins of 1,800 MHz Radio Frequency Electromagnetic Radiation Induced Damage in Mouse Immortalized Germ Cells and Spermatozoa in vitro. Front. Public Health 6:270. doi: 10.3389/fpubh.2018.00270. Copyright © 2018 Houston, Nixon, King, Aitken and De Iuliis. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).