Impact of GSM-EMW exposure on the markers of oxidative stress in fetal rat liver

" For exposed animals, results showed an increased OS reflected by high levels of malondialdehyde (MDA), a decrease in cytosolic superoxide dismutase (cytoSOD) activity, in mitochondrial superoxide dismutase (mitoSOD) levels and catalase (CAT) mRNA expression but also in hepatic nuclear factor erythroïd 2-related Factor 2 (Nrf-2), protein kinase B (Akt1), and intercellular adhesion molecule-1 (ICAM-1) mRNA expression at 15.5 dpc. Moreover, GSM-EMR exposure was shown to significantly decrease mitoSOD and CAT activities at almost all studied ages." {Credits 1}

{Credits 1} 🎪 Salameh, M., Zeitoun-Ghandour, S., Sabra, L. et al. Impact of GSM-EMW exposure on the markers of oxidative stress in fetal rat liver. Sci Rep 13, 17806 (2023). https://doi.org/10.1038/s41598-023-44814-z. © 2023 The author(s). This is an open access article under the Creative Commons Attribution 4.0 International License.